If you're playing Path of Exile 2 and want to make the most PoE 2 currency without too much hassle, picking up the right unique items is one of the smartest strategies. Some uniques can be sold for high value, traded for Exalted Orbs, Chaos Orbs, or even help you build powerful characters that make farming easier. Here are the top 5 most profitable uniques to watch out for in PoE 2, along with simple tips on how to use them to grow your currency fast.

1. Kaom’s Heart – The Tank King

Kaom’s Heart is always a top-tier unique in Path of Exile. It offers a huge life bonus, making it perfect for melee and tanky builds. In PoE 2, this item continues to be highly valuable, especially during the early weeks of a new league. Players often rush to buy it for survivability. If you’re lucky enough to loot this item, don’t vendor it! Instead, list it for trade and you could get multiple Divine Orbs or even pure PoE 2 currency. For fast sales, many players choose to buy PoE 2 currency on trusted sites like U4GM, and they’ll often trade with you directly.

2. The Headhunter – A Farming Machine

Though extremely rare, the Headhunter belt is the dream item for many. It allows players to steal monster mods, which makes farming maps much faster and more fun. Because of its power, this item sells for a huge amount of PoE 2 currency. If you find one, it could be your ticket to never worrying about currency again. You can build a fast-clearing character and farm maps quickly, collecting tons of Chaos Orbs, Orbs of Binding, and other popular currency types. People will even buy PoE 2 currency just to get this belt early.

3. Mageblood – For Easy Flask Control

Mageblood is another belt that’s incredibly profitable. It lets you keep powerful flasks active all the time. This is a favorite for both casual players and hardcore racers. In PoE 2, flask management is trickier than before, so this item is in high demand. If you manage to find Mageblood, sell it at the right time for maximum gain — early in the league or just after balance changes. This item can bring in multiple Divine Orbs and is a great way to boost your PoE 2 currency without heavy grinding.

4. Watcher’s Eye – High Value, Many Builds

Watcher’s Eye isn’t always flashy, but it's very profitable, especially when it rolls the right mods. It drops from the Elder and Uber Elder bosses, and certain aura-based mods are extremely valuable. People building support characters or min-maxing their auras will pay well for these. Try to learn which mods are most in-demand, so you don’t sell it too cheap. You can farm these bosses for profit, making it a great long-term currency strategy.

5. Void Battery – A Spell Caster’s Dream

Void Battery wands are very strong for spell builds that rely on power charges. These items are relatively easier to farm than Mageblood or Headhunter but still fetch good prices, especially in the early weeks. They can often be traded for bulk PoE 2 currency like Chaos Orbs or Orbs of Fusing, or you can use them yourself to level fast and clear content quickly. This makes it easier to farm your own currency instead of having to buy PoE 2 currency from other players or marketplaces like U4GM.

Final Tip:

To make the most of these uniques, learn how to trade properly using the in-game market or trade websites. Always check the current value using trade tools and compare offers before you accept a deal. These uniques are not just good gear — they’re opportunities to earn real value in-game. And if you want a boost, sites like U4GM offer secure, quick options to buy PoE 2 currency if you're short on time but still want to upgrade.

By keeping an eye out for these profitable items and learning how to trade wisely, you can build up your PoE 2 currency stash without spending a dime — just smart looting and timing!